Guy de Chauliac

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When the Black Death arrived in Avignon in 1348, physicians fled the city, However, Chauliac stayed on, treating plague patients and documenting symptoms meticulously. He claimed to have been himself infected and survived the disease. Through his observations, Chauliac distinguished between the two forms of the disease, the Bubonic Plague and the Pneumonic Plague. As a precautionary measure, he advised Pope Clement to keep a fire burning continuously in his chamber and to keep visitors out.

The plague was recognized as being contagious although the agent of contagion was unknown; as treatment Chauliac recommended air be purified, venesection (bleeding), and healthy diet. The outbreak of plague and widespread death was blamed on Jews, who were heretics, and in some areas were believed to have poisoned wells; Chauliac fought against this idea, using science to declare the theory untrue.